small animal ultrasound imaging system (FUJIFILM VisualSonics Inc)
86
Structured Review
FUJIFILM VisualSonics Inc
small animal ultrasound imaging system
Small Animal Ultrasound Imaging System, supplied by FUJIFILM VisualSonics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/small+animal+ultrasound+imaging+system/pmc12860263-328-1-6
Average 86 stars, based on 1 article reviews
Small Animal Ultrasound Imaging System, supplied by FUJIFILM VisualSonics Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/small+animal+ultrasound+imaging+system/pmc12860263-328-1-6
Average 86 stars, based on 1 article reviews
small animal ultrasound imaging system - by Bioz Stars,
2026-09
86/100 stars
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1) Product Images from "Apolipoprotein E knockout attenuates vascular graft fibrosis by reducing profibrotic macrophage formation through low-density lipoprotein receptor related protein 1"
Article Title: Apolipoprotein E knockout attenuates vascular graft fibrosis by reducing profibrotic macrophage formation through low-density lipoprotein receptor related protein 1
Journal: Bioactive Materials
doi: 10.1016/j.bioactmat.2026.01.029
Figure Legend Snippet: APOE KO improving mechanical properties of regenerated aortas. Ultrasound detection of native and regenerated aortas in WT and Apoe −/− rats, respectively, on Day 30 (a) and Day 90 (b). (c) M mode images of ultrasound of native and regenerated aortas in WT and Apoe −/− rats, respectively, on Day 30 and Day 90. Arrow heads indicate movement of vascular walls. Quantification of RI (d), PI (e) and compliance (f) of native and regenerated aortas in WT and Apoe −/− rats, respectively, on Day 30 and Day 90. ∗∗ indicates p < 0.01, N.S. indicates non-significant, Tukey's post-hoc test. For each time point and each group, five different images from five different animals were analyzed (n = 5). Tensile tests and elastic modulus of native and regenerated aortas in WT and Apoe −/− rats, respectively, on Day 30 (g) and Day 90 (h). ∗∗ indicates p < 0.01, Tukey's post-hoc test. For each time point and each group, five independent tests of five different samples from five different animals were conducted (n = 5).
Techniques Used:
Figure Legend Snippet: Downregulation of APOE by AAV ameliorating fibrosis during vascular regeneration after graft implantation in vivo . (a) Illustration of a strategy of adventitial delivery of AAV-shRNA(Apoe) to inhibit APOE levels in regenerated aortas after graft implantation in vivo . Two weeks after graft implantation in vivo , AAV-shRNA(Apoe) were injected into the adventitia of the regenerated aortas, which were then harvested for analysis three weeks later. (b) M mode images of ultrasound detection of regenerated aortas treated with PBS, AAV-shRNA(NC), and AAV-shRNA(Apoe) for 3 weeks. Arrow heads indicate movement of vascular walls. (c) Tensile tests of regenerated aortas treated with PBS, AAV-shRNA(NC), and AAV-shRNA(Apoe) for 3 weeks. (d) Quantification of RI, PI, and compliance of regenerated aortas treated with PBS, AAV-shRNA(NC), and AAV-shRNA(Apoe) for 3 weeks. ∗∗ indicates p < 0.01, Tukey's post-hoc test. For each group, six different images from six different animals were analyzed (n = 6). (e) Quantification of elastic modulus of regenerated aortas treated with PBS, AAV-shRNA(NC), and AAV-shRNA(Apoe) for 3 weeks. ∗∗ indicates p < 0.01, Tukey's post-hoc test. For each group, six different images from six different animals were analyzed (n = 6). (f) H&E, MTC and EVG staining of regenerated aortas treated with PBS, AAV-shRNA(NC), and AAV-shRNA(Apoe) for 3 weeks. (g) Immunofluorescence staining of COL I, COL III, elastin, αSMA, and eNOS in regenerated aortas treated with PBS, AAV-shRNA(NC), and AAV-shRNA(Apoe) for 3 weeks. L indicates lumens. Arrow heads indicate capillaries. Quantification of adventitia thickness (h), collagen positive areas according to MTC staining (i), elastin positive areas according to EVG staining (j), COL I positive areas (k), COL III positive areas (l), and number of capillaries (m) in adventitial areas of regenerated aortas. (n) Immunofluorescence staining of CTSD and CD68 in regenerated aortas treated with PBS, AAV-shRNA(NC), and AAV-shRNA(Apoe) for 3 weeks. (o) CD68 and CTSD double positive cells in regenerated aortas. ∗∗ indicates p < 0.01, Tukey's post-hoc test. For each group, six different samples from six different animals were analyzed (n = 6). (p) WB results of APOE, CTSD and SPP1 levels in regenerated aortas treated with PBS, AAV-shRNA(NC), and AAV-shRNA(Apoe) for 3 weeks and quantification of levels of APOE, CTSD and SPP1 in regenerated aortas. ∗∗ indicates p < 0.01, Tukey's post-hoc test. For each group, six different samples from six different animals were analyzed (n = 6). (q) Quantification of IGF-1 concentrations in regenerated aortas treated with PBS, AAV-shRNA(NC), and AAV-shRNA(Apoe) for 3 weeks by ELISA. ∗∗ indicates p < 0.01, Tukey's post-hoc test. For each group, six different samples from six different animals were analyzed (n = 3).
Techniques Used: In Vivo, shRNA, Injection, Staining, Immunofluorescence, Enzyme-linked Immunosorbent Assay
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